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CATH Superfamily 2.170.120.20

Ribosomal protein L25, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribosomal protein L25, beta domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ribosomal protein L25, C-terminal domain

This superfamily entry represents the C-terminal domain from the ribosomal protein L25, found in the large subunit (50S) of the bacterial ribosome. It has a mainly beta-strand structure, and it binds specifically to a portion of the 5S rRNA called loop E. The bacterial ribosomal protein L25 is bound to 5S rRNA along with L5 and L18, forming a separate domain of the ribosome. L25 (or bL25) is called TL5 in T50S (the large subunit of Thermus thermophilus,PMID:11418764 and CTC in D50S (the large ribosomal subunit of Deinococcus radiodurans). In E70S, bL25 has a single domain, in SA50S and T70S it has two domains, and in D50S the CTC protein contains three domains.

INTERPRO:IPR037121, PFAM:PF14693,PMID:11418764,PMID:10696113,PMID:26464510

GO Diversity

Unique GO annotations
5 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
11318 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 189
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 2
Unique PDBs: 188
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 21
Function
Unique EC:
Unique GO: 5
Taxonomy
Unique Species: 11318