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CATH Superfamily 1.20.120.810

Vinculin, Vh2 four-helix bundle

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vinculin, Vh2 four-helix bundle
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Vinculin, Vh2 four-helix bundle

Vinculin is a structural protein that orchestrates changes in the actin cytoskeleton following the formation of cell-matrix and cell-cell junctions. The superfamily comprises the four-helix bundle of the Vh domain (vinculin head).

GO Diversity

Unique GO annotations
88 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
443 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 9
Domain clusters (>95% seq id): 6
Domain clusters (>35% seq id): 3
Unique PDBs: 2
Alignments
Structural Clusters (5A): 3
Structural Clusters (9A): 3
FunFam Clusters: 11
Function
Unique EC:
Unique GO: 88
Taxonomy
Unique Species: 443