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CATH Superfamily 1.10.418.60

Ncd80 complex, Nuf2 subunit

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ncd80 complex, Nuf2 subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ncd80 complex, Nuf2 subunit

The name has been assigned the fact that the representative domain for this superfamily maps extremely well to a Pfam domain which belongs to a family known as Nuf2. According to the literature PMID:18455984 Nuf2 is one of the four subunits of the Ndc80 complex, an essential component of kinetochores since it comprises a point of direct contact between kinetochores and microtubules that make up the mitotic spindle and therefore has a key role in chromosome segregation.

GO Diversity

Unique GO annotations
27 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1333 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 26
Function
Unique EC:
Unique GO: 27
Taxonomy
Unique Species: 1333