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CATH Superfamily 1.10.246.130

Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain

Gamma-glutamyltranspeptidase (GGT) is a heterodimic enzyme that is generated from the precursor protein through posttranslational processing and catalyzes the hydrolysis of gamma-glutamyl bonds in gamma-glutamyl compounds. GGT has a stacked alpha-beta-beta-alpha fold comprising the large and small subunits, similar to the folds seen in members of the N-terminal nucleophile hydrolase superfamily. This entry represents the C-terminal domain of the large subunit PMID:16618936.

GO Diversity

Unique GO annotations
58 Unique GO terms

EC Diversity

Unique EC annotations
5 Unique EC terms

Species Diversity

Unique species annotations
8479 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 51
Domain clusters (>95% seq id): 6
Domain clusters (>35% seq id): 4
Unique PDBs: 33
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 29
Function
Unique EC: 5
Unique GO: 58
Taxonomy
Unique Species: 8479