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CATH Superfamily 1.10.10.1310

ToxT, HTH1 motif

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ToxT, HTH1 motif
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: ToxT, HTH1 motif

ToxT is the master virulence regulator that controls the expression of two virulence factors in Vibrio cholerae - toxin-coregulated pilus (TCP) and cholera toxin (CT), that lead to intestinal infection. This superfamily represents the HTH1 motif, which is located in close proximity to the C-terminus and plays a role in the stability and folding of the protein.

PMID:20133655,PMID:27599865

GO Diversity

Unique GO annotations
6 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
7 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 4
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Function
Unique EC:
Unique GO: 6
Taxonomy
Unique Species: 7