CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.70 | Cathepsin B; Chain A |
|
3.90.70.10 | Cysteine proteinases |
Domain Context
CATH Clusters
| Superfamily | Cysteine proteinases |
| Functional Family |
Enzyme Information
| 3.4.22.16 |
Cathepsin H.
based on mapping to UniProt O46427
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase.
-!- Present in lysosomes of mammalian cells. -!- Because of the combination of endopeptidase and aminopeptidase activity it can be considered as 'endoaminopeptidase'. -!- Belongs to peptidase family C1.
|
UniProtKB Entries (1)
| O46427 |
CATH_PIG
Sus scrofa
Pro-cathepsin H
|
PDB Structure
| PDB | 8PCH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function.
Structure
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