CATH Domain 6nxjA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.520	T-fold
	3.10.520.10	ApbE-like domains

Domain Context

CATH Clusters

Superfamily	ApbE-like domains
Functional Family	FAD:protein FMN transferase

Enzyme Information

2.7.1.180

FAD:protein FMN transferase.

based on mapping to UniProt A5F5Y3

FAD + [protein]-L-threonine = [protein]-FMN-L-threonine + AMP.

-!- The enzyme catalyzes the transfer of the FMN portion of FAD and its covalent binding to the hydroxyl group of an L-threonine residue in a target flavin-binding protein such as the B and C subunits of EC 7.2.1.1.

UniProtKB Entries (1)

A5F5Y3

APBE_VIBC3

Vibrio cholerae O395

FAD:protein FMN transferase

PDB Structure

PDB	6NXJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis. Fang, X., Osipiuk, J., Chakravarthy, S., Yuan, M., Menzer, W.M., Nissen, D., Liang, P., Raba, D.A., Tuz, K., Howard, A.J., Joachimiak, A., Minh, D.D.L., Juarez, O. J.Biol.Chem.