CATH Domain 6ncoA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.20	Apolipoprotein

Domain Context

CATH Clusters

Superfamily	Apolipoprotein
Functional Family	Apolipoprotein E

Enzyme Information

UniProtKB Entries (1)

APOE_HUMAN

Homo sapiens

Apolipoprotein E

PDB Structure

PDB	6NCO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer. Petros, A.M., Korepanova, A., Jakob, C.G., Qiu, W., Panchal, S.C., Wang, J., Dietrich, J.D., Brewer, J.T., Pohlki, F., Kling, A., Wilcox, K., Lakics, V., Bahnassawy, L., Reinhardt, P., Partha, S.K., Bodelle, P.M., Lake, M., Charych, E.I., Stoll, V.S., Sun, C., Mohler, E.G. J.Med.Chem.