CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) | |
2.40.50.140 | Nucleic acid-binding proteins |
Domain Context
CATH Clusters
Superfamily | Nucleic acid-binding proteins |
Functional Family | Eukaryotic translation initiation factor 2 subunit alpha |
Enzyme Information
UniProtKB Entries (2)
P56288 |
EI2BG_SCHPO
Schizosaccharomyces pombe 972h-
Probable translation initiation factor eIF-2B subunit gamma
|
P20459 |
IF2A_YEAST
Saccharomyces cerevisiae S288C
Eukaryotic translation initiation factor 2 subunit alpha
|
PDB Structure
PDB | 6JLZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis for eIF2B inhibition in integrated stress response.
Science
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