CATH Domain 6j3pB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q92830 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q92830

UniProtKB Entries (1)

KAT2A_HUMAN

Homo sapiens

Histone acetyltransferase KAT2A

PDB Structure

PDB	6J3P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. Huang, L., Li, H., Li, L., Niu, L., Seupel, R., Wu, C., Cheng, W., Chen, C., Ding, B., Brennan, P.E., Yang, S. J.Med.Chem.