CATH Domain 6gomE00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

RASK_HUMAN

Homo sapiens

GTPase KRas

PDB Structure

PDB	6GOM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Cruz-Migoni, A., Canning, P., Quevedo, C.E., Bataille, C.J.R., Bery, N., Miller, A., Russell, A.J., Phillips, S.E.V., Carr, S.B., Rabbitts, T.H. Proc. Natl. Acad. Sci. U.S.A.