CATH Domain 6fpoM00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.645	Cytochrome-c3 Hydrogenase; chain B
	1.10.645.10	Cytochrome-c3 Hydrogenase, chain B

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 Hydrogenase, chain B
Functional Family	Hydrogenase 2 large subunit

Enzyme Information

1.12.99.6

Hydrogenase (acceptor).

based on mapping to UniProt P0ACD8

H(2) + A = AH(2).

-!- Uses molecular hydrogen for the reduction of a variety of substances.

UniProtKB Entries (2)

P0ACD8	MBHL_ECOLI Escherichia coli K-12 Hydrogenase-1 large chain
P69740	MBHS_ECOL6 Escherichia coli CFT073 Hydrogenase-1 small chain

PDB Structure

PDB	6FPO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanistic Exploitation of a Self-Repairing, Blocked Proton Transfer Pathway in an O2-Tolerant [NiFe]-Hydrogenase. Evans, R.M., Ash, P.A., Beaton, S.E., Brooke, E.J., Vincent, K.A., Carr, S.B., Armstrong, F.A. J. Am. Chem. Soc.