CATH Domain 6eb1A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family

Enzyme Information

UniProtKB Entries (1)

F2WR52_9HIV1

Human immunodeficiency virus 1

Integrase

PDB Structure

PDB	6EB1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	An Isoquinoline Scaffold as a Novel Class of Allosteric HIV-1 Integrase Inhibitors. Wilson, T.A., Koneru, P.C., Rebensburg, S.V., Lindenberger, J.J., Kobe, M.J., Cockroft, N.T., Adu-Ampratwum, D., Larue, R.C., Kvaratskhelia, M., Fuchs, J.R. ACS Med Chem Lett