CATH Classification

Domain Context

CATH Clusters

Superfamily HAD superfamily/HAD-like
Functional Family Carboxy-terminal domain RNA polymerase II polypeptide A small

Enzyme Information

UniProtKB Entries (2)

Q13127
REST_HUMAN
Homo sapiens
RE1-silencing transcription factor
A0A1S2ZIM2
A0A1S2ZIM2_ERIEU
Erinaceus europaeus
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X1

PDB Structure

PDB 6DU2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
Burkholder, N.T., Mayfield, J.E., Yu, X., Irani, S., Arce, D.K., Jiang, F., Matthews, W.L., Xue, Y., Zhang, Y.J.
J. Biol. Chem.
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