CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.533 | Death Domain, Fas |
|
1.10.533.10 | Death Domain, Fas |
Domain Context
CATH Clusters
| Superfamily | Death Domain, Fas |
| Functional Family | Apoptosis-associated speck-like protein containing a CARD |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
| PDB | 6DRN |
| External Links | |
| Method | ELECTRON MICROSCOPY |
| Organism | |
| Primary Citation |
Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A.
|
