CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Putative lysine-specific demethylase 5b

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt P29375

UniProtKB Entries (1)

P29375
KDM5A_HUMAN
Homo sapiens
Lysine-specific demethylase 5A

PDB Structure

PDB 6DQ9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.
Horton, J.R., Woodcock, C.B., Chen, Q., Liu, X., Zhang, X., Shanks, J., Rai, G., Mott, B.T., Jansen, D.J., Kales, S.C., Henderson, M.J., Cyr, M., Pohida, K., Hu, X., Shah, P., Xu, X., Jadhav, A., Maloney, D.J., Hall, M.D., Simeonov, A., Fu, H., Vertino, P.M., Cheng, X.
J. Med. Chem.