CATH Classification

Domain Context

CATH Clusters

Superfamily Endonuclease Chain A
Functional Family Tyrosyl-DNA phosphodiesterase 1

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 6DJH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.
Lountos, G.T., Zhao, X.Z., Kiselev, E., Tropea, J.E., Needle, D., Pommier, Y., Burke, T.R., Waugh, D.S.
Nucleic Acids Res.
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