CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 6BVH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Potent, multi-target serine protease inhibition achieved by a simplified beta-sheet motif.
Chen, X., Riley, B.T., de Veer, S.J., Hoke, D.E., Van Haeften, J., Leahy, D., Swedberg, J.E., Brattsand, M., Hartfield, P.J., Buckle, A.M., Harris, J.M.
PLoS ONE