CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P31749
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P49841
GSK3B_HUMAN
Homo sapiens
Glycogen synthase kinase-3 beta

PDB Structure

PDB 6BUU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Chu, N., Salguero, A.L., Liu, A.Z., Chen, Z., Dempsey, D.R., Ficarro, S.B., Alexander, W.M., Marto, J.A., Li, Y., Amzel, L.M., Gabelli, S.B., Cole, P.A.
Cell