CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.150 | C2 domain |
Domain Context
CATH Clusters
| Superfamily | C2 domain |
| Functional Family | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
Enzyme Information
| 2.7.1.154 |
Phosphatidylinositol-4-phosphate 3-kinase.
based on mapping to UniProt O00443
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 3,4-bisphosphate.
-!- This enzyme also phosphorylates PtdIns to PtdIns3P.
|
UniProtKB Entries (1)
| O00443 |
P3C2A_HUMAN
Homo sapiens
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
|
PDB Structure
| PDB | 6BTZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure
|
