CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.30 | SH3 type barrels. |
|
2.30.30.140 |
Domain Context
CATH Clusters
| Superfamily | 2.30.30.140 |
| Functional Family | Histone-lysine N-methyltransferase |
Enzyme Information
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q15047
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
| Q15047 |
SETB1_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETDB1
|
PDB Structure
| PDB | 6BHH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun
|