1 keywords

CATH Domain 6bgyA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.650 Cupin

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Putative lysine-specific demethylase 5b

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt P29375

UniProtKB Entries (1)

P29375
KDM5A_HUMAN
Homo sapiens
Lysine-specific demethylase 5A

PDB Structure

PDB 6BGY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.
Horton, J.R., Liu, X., Wu, L., Zhang, K., Shanks, J., Zhang, X., Rai, G., Mott, B.T., Jansen, D.J., Kales, S.C., Henderson, M.J., Pohida, K., Fang, Y., Hu, X., Jadhav, A., Maloney, D.J., Hall, M.D., Simeonov, A., Fu, H., Vertino, P.M., Yan, Q., Cheng, X.
J. Med. Chem.