CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Cyclin-K (Predicted)

Enzyme Information

UniProtKB Entries (1)

Q9NYV4
CDK12_HUMAN
Homo sapiens
Cyclin-dependent kinase 12

PDB Structure

PDB 6B3E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Design of Selective Noncovalent CDK12 Inhibitors.
Johannes, J.W., Denz, C.R., Su, N., Wu, A., Impastato, A.C., Mlynarski, S., Varnes, J.G., Prince, D.B., Cidado, J., Gao, N., Haddrick, M., Jones, N.H., Li, S., Li, X., Liu, Y., Nguyen, T.B., O'Connell, N., Rivers, E., Robbins, D.W., Tomlinson, R., Yao, T., Zhu, X., Ferguson, A.D., Lamb, M.L., Manchester, J.I., Guichard, S.
ChemMedChem