CATH Domain 6b30A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Nuclear orphan receptor ROR-beta

Enzyme Information

UniProtKB Entries (1)

RORG_HUMAN

Homo sapiens

Nuclear receptor ROR-gamma

PDB Structure

PDB	6B30
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of orally efficacious ROR gamma t inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds. Shirai, J., Tomata, Y., Kono, M., Ochida, A., Fukase, Y., Sato, A., Masada, S., Kawamoto, T., Yonemori, K., Koyama, R., Nakagawa, H., Nakayama, M., Uga, K., Shibata, A., Koga, K., Okui, T., Shirasaki, M., Skene, R., Sang, B., Hoffman, I., Lane, W., Fujitani, Y., Yamasaki, M., Yamamoto, S. Bioorg. Med. Chem.