CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.840 | Son of Sevenless (SoS) protein; Chain S, domain 2 |
|
1.10.840.10 | Ras guanine-nucleotide exchange factors catalytic domain |
Domain Context
CATH Clusters
| Superfamily | Ras guanine-nucleotide exchange factors catalytic domain |
| Functional Family | Ras guanyl-releasing protein 3 isoform 1 |
Enzyme Information
UniProtKB Entries (1)
| P01112 |
RASH_HUMAN
Homo sapiens
GTPase HRas
|
PDB Structure
| PDB | 6AXG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Elife
|
