CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Adenine phosphoribosyltransferase

Enzyme Information

2.4.2.7
Adenine phosphoribosyltransferase.
based on mapping to UniProt Q5NII9
AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- 5-amino-4-imidazolecarboxamide can replace adenine.

UniProtKB Entries (1)

Q5NII9
APT_FRATT
Francisella tularensis subsp. tularensis SCHU S4
Adenine phosphoribosyltransferase

PDB Structure

PDB 5YW5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of APRT from Francisella tularensis - an N-H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases.
Pavithra, G.C., Ramagopal, U.A.
FEBS J.