CATH Domain 5yveA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.490	atp-gated p2x4 ion channel fold
	2.60.490.10	atp-gated p2x4 ion channel domain

Domain Context

CATH Clusters

Superfamily	atp-gated p2x4 ion channel domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

P2RX3_HUMAN

Homo sapiens

P2X purinoceptor 3

PDB Structure

PDB	5YVE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Druggable negative allosteric site of P2X3 receptors. Wang, J., Wang, Y., Cui, W.W., Huang, Y., Yang, Y., Liu, Y., Zhao, W.S., Cheng, X.Y., Sun, W.S., Cao, P., Zhu, M.X., Wang, R., Hattori, M., Yu, Y. Proc. Natl. Acad. Sci. U.S.A.