CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Platelet-activating factor acetylhydrolase |
Enzyme Information
| 3.1.1.47 |
1-alkyl-2-acetylglycerophosphocholine esterase.
based on mapping to UniProt Q13093
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.
|
UniProtKB Entries (1)
| Q13093 |
PAFA_HUMAN
Homo sapiens
Platelet-activating factor acetylhydrolase
|
PDB Structure
| PDB | 5YEA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.
J. Med. Chem.
|
