CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.630 | Cytochrome p450 |
|
1.10.630.10 | Cytochrome P450 |
Domain Context
CATH Clusters
| Superfamily | Cytochrome P450 |
| Functional Family | Cytochrome P450 monooxygenase |
Enzyme Information
| 1.7.1.14 |
Nitric oxide reductase (NAD(P)(+), nitrous oxide-forming).
based on mapping to UniProt P23295
Nitrous oxide + NAD(P)(+) + H(2)O = 2 nitric oxide + NAD(P)H.
-!- The enzyme from Fusarium oxysporum utilizes only NADH, but the isozyme from Trichosporon cutaneum utilizes both NADH and NADPH. -!- The electron transfer from NAD(P)H to heme occurs directly, not requiring flavin or other redox cofactors.
|
UniProtKB Entries (1)
| P23295 |
NOR_FUSOX
Fusarium oxysporum
NADP nitrous oxide-forming nitric oxide reductase
|
PDB Structure
| PDB | 5Y5G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun
|
