CATH Domain 5wuuA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

BRD4_HUMAN

Homo sapiens

Bromodomain-containing protein 4

PDB Structure

PDB	5WUU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays. Sun, Z., Zhang, H., Chen, Z., Xie, Y., Jiang, H., Chen, L., Ding, H., Zhang, Y., Jiang, H., Zheng, M., Luo, C. Bioorg. Med. Chem. Lett.