CATH Classification

Domain Context

CATH Clusters

Superfamily Mu homology domain, subdomain B
Functional Family Putative AP-2 complex subunit mu

Enzyme Information

UniProtKB Entries (1)

P35570
IRS1_RAT
Rattus norvegicus
Insulin receptor substrate 1

PDB Structure

PDB 5WRL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Yoneyama, Y., Lanzerstorfer, P., Niwa, H., Umehara, T., Shibano, T., Yokoyama, S., Chida, K., Weghuber, J., Hakuno, F., Takahashi, S.I.
Elife