CATH Classification

Domain Context

CATH Clusters

Superfamily Insulin-like
Functional Family

Enzyme Information

UniProtKB Entries (1)

P01308
INS_HUMAN
Homo sapiens
Insulin

PDB Structure

PDB 5WDM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.
Glidden, M.D., Aldabbagh, K., Phillips, N.B., Carr, K., Chen, Y.S., Whittaker, J., Phillips, M., Wickramasinghe, N.P., Rege, N., Swain, M., Peng, Y., Yang, Y., Lawrence, M.C., Yee, V.C., Ismail-Beigi, F., Weiss, M.A.
J. Biol. Chem.