CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

P55285
CADH6_HUMAN
Homo sapiens
Cadherin-6

PDB Structure

PDB 5VEB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Bialucha, C.U., Collins, S.D., Li, X., Saxena, P., Zhang, X., Durr, C., Lafont, B., Prieur, P., Shim, Y., Mosher, R., Lee, D., Ostrom, L., Hu, T., Bilic, S., Rajlic, I.L., Capka, V., Jiang, W., Wagner, J.P., Elliott, G., Veloso, A., Piel, J.C., Flaherty, M.M., Mansfield, K.G., Meseck, E.K., Rubic-Schneider, T., London, A.S., Tschantz, W.R., Kurz, M., Nguyen, D., Bourret, A., Meyer, M.J., Faris, J.E., Janatpour, M.J., Chan, V.W., Yoder, N.C., Catcott, K.C., McShea, M.A., Sun, X., Gao, H., Williams, J., Hofmann, F., Engelman, J.A., Ettenberg, S.A., Sellers, W.R., Lees, E.
Cancer Discov