CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.250.1570
Functional Family

Enzyme Information

UniProtKB Entries (1)

J9VSX1
J9VSX1_CRYNH
Cryptococcus neoformans var. grubii H99
Adenylosuccinate lyase

PDB Structure

PDB 5V4L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
Chitty, J.L., Blake, K.L., Blundell, R.D., Koh, Y.Q.A.E., Thompson, M., Robertson, A.A.B., Butler, M.S., Cooper, M.A., Kappler, U., Williams, S.J., Kobe, B., Fraser, J.A.
J. Biol. Chem.