CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.200 | Fumarase C; Chain A, domain 2 |
|
1.20.200.10 | Fumarase/aspartase (Central domain) |
Domain Context
CATH Clusters
| Superfamily | Fumarase/aspartase (Central domain) |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| J9VSX1 |
J9VSX1_CRYNH
Cryptococcus neoformans var. grubii H99
Adenylosuccinate lyase
|
PDB Structure
| PDB | 5V4L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
J. Biol. Chem.
|