CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P15531
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P15531
NDKA_HUMAN
Homo sapiens
Nucleoside diphosphate kinase A

PDB Structure

PDB 5UI4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
"Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
Mortenson, D.E., Brighty, G.J., Plate, L., Bare, G., Chen, W., Li, S., Wang, H., Cravatt, B.F., Forli, S., Powers, E.T., Sharpless, K.B., Wilson, I.A., Kelly, J.W.
J. Am. Chem. Soc.