CATH Domain 5u2nA02

Superfamily	Aldolase class I
Functional Family

2.4.2.12

Nicotinamide phosphoribosyltransferase.

based on mapping to UniProt P43490

Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho- alpha-D-ribose 1-diphosphate.

NAMPT_HUMAN

Homo sapiens

Nicotinamide phosphoribosyltransferase

PDB	5U2N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. Wilsbacher, J.L., Cheng, M., Cheng, D., Trammell, S.A.J., Shi, Y., Guo, J., Koeniger, S.L., Kovar, P.J., He, Y., Selvaraju, S., Heyman, H.R., Sorensen, B.K., Clark, R.F., Hansen, T.M., Longenecker, K.L., Raich, D., Korepanova, A.V., Cepa, S., Towne, D.L., Abraham, V.C., Tang, H., Richardson, P.L., McLoughlin, S.M., Badagnani, I., Curtin, M.L., Michaelides, M.R., Maag, D., Buchanan, F.G., Chiang, G.G., Gao, W., Rosenberg, S.H., Brenner, C., Tse, C. Mol. Cancer Ther.