CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.605 | Aldehyde Dehydrogenase; Chain A, domain 1 |
|
3.40.605.10 | Aldehyde Dehydrogenase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aldehyde Dehydrogenase; Chain A, domain 1 |
| Functional Family | N-succinylglutamate 5-semialdehyde dehydrogenase |
Enzyme Information
| 1.2.1.71 |
Succinylglutamate-semialdehyde dehydrogenase.
based on mapping to UniProt A1U5W8
N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H(2)O = N-succinyl-L- glutamate + NADH.
-!- This is the fourth enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine. -!- This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. -!- The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
|
UniProtKB Entries (1)
| A1U5W8 |
ASTD_MARHV
Marinobacter hydrocarbonoclasticus VT8
N-succinylglutamate 5-semialdehyde dehydrogenase
|
PDB Structure
| PDB | 5U0L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Five Fatty Aldehyde Dehydrogenase Enzymes from Marinobacter and Acinetobacter spp. and Structural Insights into the Aldehyde Binding Pocket.
Appl. Environ. Microbiol.
|