CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.360 | Dihydrodipicolinate Reductase; domain 2 |
|
3.30.360.50 | S-adenosylmethionine decarboxylase |
Domain Context
CATH Clusters
| Superfamily | S-adenosylmethionine decarboxylase |
| Functional Family | S-adenosylmethionine decarboxylase proenzyme |
Enzyme Information
| 4.1.1.50 |
Adenosylmethionine decarboxylase.
based on mapping to UniProt Q587A7
S-adenosyl-L-methionine = S-adenosyl 3-(methylthio)propylamine + CO(2).
|
UniProtKB Entries (1)
| Q587A7 |
Q587A7_TRYB2
Trypanosoma brucei brucei TREU927
S-adenosylmethionine decarboxylase proenzyme
|
PDB Structure
| PDB | 5TVO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
Elife
|
