CATH Domain 5th6B00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	72 kDa type IV collagenase

Enzyme Information

3.4.24.35

Gelatinase B.

based on mapping to UniProt P14780

Cleavage of gelatin types I and V and collagen types IV and V.

-!- Belongs to peptidase family M10B.

UniProtKB Entries (1)

MMP9_HUMAN

Homo sapiens

Matrix metalloproteinase-9

PDB Structure

PDB	5TH6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9. Appleby, T.C., Greenstein, A.E., Hung, M., Liclican, A., Velasquez, M., Villasenor, A.G., Wang, R., Wong, M.H., Liu, X., Papalia, G.A., Schultz, B.E., Sakowicz, R., Smith, V., Kwon, H.J. J. Biol. Chem.