CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.620 | Ribonucleotide Reductase, subunit A |
|
1.10.620.20 | Ribonucleotide Reductase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Ribonucleotide Reductase, subunit A |
| Functional Family |
Enzyme Information
| 1.14.13.236 |
Toluene 4-monooxygenase.
based on mapping to UniProt Q00460
Toluene + NADH + O(2) = 4-methylphenol + NAD(+) + H(2)O.
-!- This bacterial enzyme belongs to a family of soluble diiron hydroxylases that includes toluene-, benzene-, xylene- and methane monooxygenases, phenol hydroxylases, and alkene epoxidases. -!- The enzyme comprises a four-component complex that includes a hydroxylase, NADH-ferredoxin oxidoreductase, a Rieske-type [2Fe-2S] ferredoxin, and an effector protein.
|
UniProtKB Entries (1)
| Q00457 |
TMOB_PSEME
Pseudomonas mendocina
Toluene-4-monooxygenase system, hydroxylase component subunit gamma
|
PDB Structure
| PDB | 5TDS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
In-crystal reaction cycle of a toluene-bound diiron hydroxylase.
Nature
|