CATH Domain 5tbmA00

Superfamily	PAS domain
Functional Family	Hypoxia-inducible factor 1-alpha isoform 1

EPAS1_HUMAN

Homo sapiens

Endothelial PAS domain-containing protein 1

PDB	5TBM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma. Wallace, E.M., Rizzi, J.P., Han, G., Wehn, P.M., Cao, Z., Du, X., Cheng, T., Czerwinski, R.M., Dixon, D.D., Goggin, B.S., Grina, J.A., Halfmann, M.M., Maddie, M.A., Olive, S.R., Schlachter, S.T., Tan, H., Wang, B., Wang, K., Xie, S., Xu, R., Yang, H., Josey, J.A. Cancer Res.