CATH Domain 5om9A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.340	Metallocarboxypeptidase-like

Domain Context

CATH Clusters

Superfamily	Metallocarboxypeptidase-like
Functional Family	Carboxypeptidase A5

Enzyme Information

3.4.17.1

Carboxypeptidase A.

based on mapping to UniProt P15085

Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.

-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (1)

P15085

CBPA1_HUMAN

Homo sapiens

Carboxypeptidase A1

PDB Structure

PDB	5OM9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library. Testero, S.A., Granados, C., Fernandez, D., Gallego, P., Covaleda, G., Reverter, D., Vendrell, J., Aviles, F.X., Pallares, I., Mobashery, S. ACS Med Chem Lett