CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.15 | Metallo-beta-lactamase; Chain A |
|
3.60.15.10 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
| Functional Family | Class B metallo-beta-lactamase |
Enzyme Information
UniProtKB Entries (1)
| Q9K2N0 |
Q9K2N0_PSEAI
Pseudomonas aeruginosa
Beta-lactamase class B VIM-2
|
PDB Structure
| PDB | 5MXR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
SAR Studies Leading to the Identification of a Novel Series of Metallo-beta-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
Acs Infect Dis.
|