CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1440 | Tubulin/FtsZ, GTPase domain |
Domain Context
CATH Clusters
Superfamily | Tubulin/FtsZ, GTPase domain |
Functional Family | Tubulin alpha chain |
Enzyme Information
UniProtKB Entries (3)
E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
P63043 |
STMN4_RAT
Rattus norvegicus
Stathmin-4
|
Q6B856 |
TBB2B_BOVIN
Bos taurus
Tubulin beta-2B chain
|
PDB Structure
PDB | 5M7E |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Nat Commun
|