CATH Domain 5m70F00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.555	Phosphatidylinositol 3-kinase; Chain A
	1.10.555.10	Rho GTPase activation protein

Domain Context

CATH Clusters

Superfamily	Rho GTPase activation protein
Functional Family	Rho GTPase-activating protein 1

Enzyme Information

UniProtKB Entries (1)

RHOA_HUMAN

Homo sapiens

Transforming protein RhoA

PDB Structure

PDB	5M70
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Assessing the Influence of Mutation on GTPase Transition States by Using X-ray Crystallography, (19) F NMR, and DFT Approaches. Jin, Y., Molt, R.W., Pellegrini, E., Cliff, M.J., Bowler, M.W., Richards, N.G.J., Blackburn, G.M., Waltho, J.P. Angew. Chem. Int. Ed. Engl.