CATH Domain 5m1iA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.70	Aldolase class I

Domain Context

CATH Clusters

Superfamily	Aldolase class I
Functional Family	Alpha-galactosidase

Enzyme Information

3.2.1.22

Alpha-galactosidase.

based on mapping to UniProt G4FEF4

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.

-!- Also hydrolyzes alpha-D-fucosides.

UniProtKB Entries (1)

G4FEF4

AGAL_THEMA

Thermotoga maritima MSB8

Alpha-galactosidase

PDB Structure

PDB	5M1I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Adamson, C., Pengelly, R.J., Shamsi Kazem Abadi, S., Chakladar, S., Draper, J., Britton, R., Gloster, T.M., Bennet, A.J. Angew.Chem.Int.Ed.Engl.