CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Dipeptidase gliJ

Enzyme Information

3.4.13.19
Membrane dipeptidase.
based on mapping to UniProt Q4WMJ8
Hydrolysis of dipeptides.
-!- Membrane bound, with broad specificity. -!- Abundant in the kidney cortex. -!- Inhibited by bestatin and cilastatin. -!- Belongs to peptidase family M19. -!- Formerly EC 3.4.3.1, EC 3.4.3.2, EC 3.4.3.6, EC 3.4.13.1, EC 3.4.13.2, EC 3.4.13.8, EC 3.4.13.11 and EC 3.4.13.15.

UniProtKB Entries (1)

Q4WMJ8
GLIJ_ASPFU
Aspergillus fumigatus Af293
Dipeptidase gliJ

PDB Structure

PDB 5LX7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ.
Marion, A., Groll, M., Scharf, D.H., Scherlach, K., Glaser, M., Sievers, H., Schuster, M., Hertweck, C., Brakhage, A.A., Antes, I., Huber, E.M.
ACS Chem. Biol.