CATH Classification

Domain Context

CATH Clusters

Superfamily Arenavirus RNA polymerase
Functional Family RNA-directed RNA polymerase L

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt P14240
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
3.1.-.-
Acting on ester bonds.
based on mapping to UniProt P14240

UniProtKB Entries (1)

P14240
L_LYCVA
Lymphocytic choriomeningitis virus (strain Armstrong)
RNA-directed RNA polymerase L

PDB Structure

PDB 5LTN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of Lymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
Saez-Ayala, M., Yekwa, E.L., Carcelli, M., Canard, B., Alvarez, K., Ferron, F.
Iucrj