CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 |
|
1.20.58.1610 | NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 |
Domain Context
CATH Clusters
| Superfamily | NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 |
| Functional Family | NADH-quinone oxidoreductase subunit A |
Enzyme Information
| 7.1.1.2 |
NADH:ubiquinone reductase (H(+)-translocating).
based on mapping to UniProt O78753
NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
-!- The complex is present in mitochondria and aerobic bacteria. -!- Breakdown of the complex can release EC 1.6.99.3. -!- In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH. -!- Formerly EC 1.6.5.3.
|
UniProtKB Entries (2)
| W5NRY1 |
W5NRY1_SHEEP
Ovis aries
Uncharacterized protein
|
| P23934 |
NDUS6_BOVIN
Bos taurus
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
|
PDB Structure
| PDB | 5LNK |
| External Links | |
| Method | ELECTRON MICROSCOPY |
| Organism | |
| Primary Citation |
Atomic structure of the entire mammalian mitochondrial complex I.
Nature
|
